When the labyrinthine spaces are invaded by suppuration, there is at first an irritation produced which sets up a nystagmus, and as the process of destruction goes on the labyrinthine fluids coagulate, so that motions which are ordinarily set up by experimental irritation no longer take place; the stimuli, therefore, fail to reach the vestibular nerve and ocular motor centre, and nystagmus is no longer produced.
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